Metachronous splenic metastasis in an anal squamous cell carcinoma

Although the spleen is a highly vascularised organ, metastasis remains a very rare situation, with an inci- dence ranged between 0.3 and 7.3% (1). They mainly occur in a context of multivisceral metastatic cancer at terminal stage and present as multiple and asymptomatic lesions diagnosed by incidental radiological assessment performed either in the regular follow-up of patients with cancer or in the workup at the time of the primary tumor diagnosis. Anal squamous cell carcinoma (ASCC), a rel- atively rare gastrointestinal malignancy, mainly associat- ed with liver and lymph nodes metastases, has not been described yet as a potential primary tumor associated with spleen metastases (2).